Naloxone, Nalmefene, and Naltrexone: Is There a Need for Three Opioid Antagonists?
Developed in Collaboration with the American College of Medical Toxicology

Sunday, April 7, 2024

8:30 AM – 9:45 AM

Presenter(s)

Lewis S. Nelson, MD, MBA, FASAM

Chair
Rutgers New Jersey Medical School, New Jersey

Slides
ES

Evan S. Schwarz, MD

Associate Professor
UCLA, California
JoAn Laes, MD, DFASAM

Addiction Medicine Physician, Medical Toxicologist
Allina Health, Minnesota
Robert Cole Pueringer, MD, FASAM

Medical Toxicologist, Addiction Medicine Specialist, Hospitalist
Essentia Health, Minnesota

Non-presenting author(s)

Jeanmarie Perrone, MD

Professor of Emergency Medicine, Director of the Center for Addiction Medicine and Policy
University of Pennsylvania, Pennsylvania
RW

Rachel S. Wightman, MD, FACMT

Associate Professor
Alpert Medical School of Brown University, Rhode Island

An improved understanding of the clinical pharmacology of naloxone, nalmefene, and related agents will provide attendees with the tools to choose among various opioid antagonist products and formulations and provide targeted, efficient, safe overdose management to patients with acute opioid overdose or precipitated opioid withdrawal.

Learning Objectives:

Learners will be able to:

Describe the pharmacology of naloxone, nalmefene, naltrexone, and buprenorphine including their pharmacokinetic profiles
Discuss the clinical risk and benefit of the various opioid reversal agents in the management of patients following an opioid overdose with special attention to patients using fentanyl and nitazenes.
Explain the risk and treatment of precipitated withdrawal in the acute care setting, including the use of buprenorphine.

Naloxone, Nalmefene, and Naltrexone: Is There a Need for Three Opioid Antagonists?Developed in Collaboration with the American College of Medical Toxicology

Presenter(s)

Non-presenting author(s)

Learning Objectives:

Naloxone, Nalmefene, and Naltrexone: Is There a Need for Three Opioid Antagonists?
Developed in Collaboration with the American College of Medical Toxicology